What is a murine monoclonal antibody?

What is a murine monoclonal antibody? Murine monoclonal antibodies are so called due to their origin from rodent hosts, more commonly mice and rats from the Muridae family. Today, we know that patients treated with native murine antibodies develop an allergic reaction to these molecules termed human anti-mouse or anti-murine antibody (HAMA) response. Which of … Continue reading What is a murine monoclonal antibody?